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Ferroptosis is defined by a unique redox imbalance driven primarily through enzymatic or iron-dependent lipid peroxidation and loss of antioxidant membrane repair resulting in membrane rupture and cell death

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While N-(4-hydroxyphenyl) retinamide (4-HPR), a derivative of RA, is a potent chemopreventive and antiproliferative agent against various cancers [200, 201]

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The CD44hyaluronic acid interaction is dominated by an extensive interaction network with the predominantly aliphatic residues that line the hook and a stretch of aromatic and basic amino acids located at the base of the groove (Fig

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